On October 28, 2024, Prof. Yong Qin from Sichuan University was invited by State Key Laboratory of Elemento-organic Chemistry to visit on Nankai Lectureship on Organic Chemistry. Prof. Qin gave an academic lecture entitled “Precision Synthesis-Oriented Total Synthesis of Natural Products: From Basic Research to Industrial Applications” in Shixian Building. The lecture was hosted by Prof. Jianhua Xie, deputy Director of the Key Laboratory, and attracted nearly 150 participants from the Key Laboratory and the College of Chemistry.
At the beginning, Prof. Chunming Cui, Director of the Key Laboratory, presented the certificate of “Nankai Lectureship on Organic Chemistry” to Prof. Qin. Then Prof. Qin Yong introduced his team's synthetic methods and strategies of representative cyclopropanation tandem reaction starting from the important role of total synthesis of natural products in the process of new drug discovery. By using these methods and strategies, his team has accomplished the challenging total synthesis of more than 100 natural products and drugs, including complex indole alkaloids and diterpene alkaloids. In addition, Prof. Qin also demonstrated the contribution of total synthesis research in serving people's life&health and revolutionizing drug synthesis process routes, and shared his team's exploration of industrializing of natural drugs with complex structures and high industrial manufacturing difficulties, such as orlistat, a good drug for weight-reduction, and sulfadiazepine sodium, an excellent anticoagulant drug.
After the presentation, Prof. Qin had a warm and in-depth interaction with the students and teachers present. He patiently and carefully answered the cutting-edge research and the actual production process of the field of questions from teachers and students, and attendants highly appreciated Prof. Qin's work on total synthesis in promoting high-quality and low-cost drug research and development.
Yong Qin, Changjiang Scholar & Distinguished Professor of the Ministry of Education of China, National Outstanding Young Scientist Funder, and Fellow of the Chinese Chemical Society. He received his bachelor’s degree from Department of Chemistry, Yunnan University in 1989, and received his Ph.D. degree from the Chengdu Institute of Organic Chemistry of the Chinese Academy of Sciences in 1995. From 1995 to 1996, he was a Research Associate at Chengdu Institute of Organic Chemistry of Chinese Academy of Sciences. And from 1996 to 2000, he was a Postdoctoral Fellow of the Department of Chemistry, University of Vermont, USA. From 2000 to 2003, he was a Research Scientist at Triad Therapeutics Inc. in San Diego, USA. From 2003 to present, he is a Professor at West China School of Pharmaceutical Sciences, Sichuan University, China. He is the vice chairman of the Specialized Committee on Pharmaceutical Processing of the Chinese Chemical Society and a member of the Pharmaceutical Discipline Review Group of the State Council. Prof. Qin was awarded the Second Prize of National Technology Invention Award, the First Prize of Natural Science of the Ministry of Education of China, Wu Jieping Pharmaceutical Innovation Award and Wu Jieping-Paul Janssen Medical Pharmacology Award, the First Weisan Natural Product Synthesis Award of the Chinese Chemical Society, and the Yiling Biomedical Innovation Award of the Chinese Pharmaceutical Society. He has presided over the innovation groups, major projects, key projects, and major scientific and technological special projects for the creation and manufacture of new drugs. He is mainly engaged in the research of total synthesis and medicinal chemistry of natural products with important physiological activities.
