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Under the request of Marshal Rongzhen Nie and China’s renowned chemist Shixian Yang, the State Key Laboratory of Elemento-organic Chemistry (SKLEOC) was founded by pioneering Chinese scientists including organic chemist Prof. Ruyu Chen and pesticide chemist Prof. Zhengming Li. Established in 1985, the SKLEOC was examined and accepted by the state government and officially opened to the public in 1987. The SKLEOC stands as one of the first state key laboratories of the China. At the end of 2024, the SKLEOC was reorganized under the national key laboratory system.